Immune cell metabolism plays a pivotal role in shaping and modulating immune responses.The metabolic state of immune cells influences their development, activation, differentiation, and overall function, impacting both innate and adaptive immunity.While glycolysis is crucial for activation and effector Decanter function of CD8 T cells, regulatory T

BackgroundThe global burden of chronic respiratory diseases (CRDs) disproportionally affects Roma populations.Health interventions addressing CRD among Roma or other vulnerable groups often fail to be effective, as their implementation strategy misaligns with the local context.To design context-driven strategies, we studied CRD-related beliefs, per

This study investigated the effect of various layer arrangements and their impact on the properties of laminated veneer lumber (LVL).Seven different layer arrangements (CCCCCCC, DDDDDDD, PPPPPPP, CDDDDDC, CPPPPPC, Flour CDDCDDC, CPPCPPC, CDCDCDC, CPCPCPC, CCDDDCC, CCPPPCC, CCDCDCC, and CCPCPCC) were used in the manufacturing of the LVL, with each a

Nephrotic syndrome (NS) is a complex clinical entity characterized by proteinuria, hypoalbuminemia, and edema.In this review, we propose the view of NS as a podocytopathy, highlighting the importance of understanding the role of podocytes in the development of this condition.We discuss the various etiologies of NS, ranging from congenital to primar

The inhibitors of mammalian target of rapapmycin (mTOR), everolimus, temsirolimus and rapamycin, have a wide range of clinical utility; however, as is inevitably the case with other chemotherapeutic agents, resistance development constrains their effectiveness.One putative mechanism of resistance is the promotion of autophagy, which is a direct con